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Marcello Maggiolini Selected Research

G-Protein-Coupled Receptors (Receptors, G Protein Coupled)

12/2018GPCR Modulation in Breast Cancer.
12/2017G Protein-Coupled Receptors at the Crossroad between Physiologic and Pathologic Angiogenesis: Old Paradigms and Emerging Concepts.
6/2017Pharmacotherapeutic Targeting of G Protein-Coupled Receptors in Oncology: Examples of Approved Therapies and Emerging Concepts.
4/2016Response to "Comment on 'Effects of Atrazine on Estrogen Receptor 〈- and G Protein-Coupled Receptor 30-Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts'".
3/2016Recent Advances on the Role of G Protein-Coupled Receptors in Hypoxia-Mediated Signaling.
1/2016Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands.
10/2015A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models.
5/2015Effects of atrazine on estrogen receptor α- and G protein-coupled receptor 30-mediated signaling and proliferation in cancer cells and cancer-associated fibroblasts.
8/2014GPER mediates activation of HIF1α/VEGF signaling by estrogens.
1/2014GPER activates Notch signaling in breast cancer cells and cancer-associated fibroblasts (CAFs).
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Marcello Maggiolini Research Topics

Disease

86Neoplasms (Cancer)
01/2022 - 07/2002
76Breast Neoplasms (Breast Cancer)
06/2022 - 07/2002
10Neoplasm Metastasis (Metastasis)
01/2022 - 01/2011
9Hypoxia (Hypoxemia)
01/2022 - 01/2011
8Triple Negative Breast Neoplasms
06/2022 - 01/2014
6Carcinogenesis
02/2021 - 05/2004
6Prostatic Neoplasms (Prostate Cancer)
12/2017 - 11/2002
4Ovarian Neoplasms (Ovarian Cancer)
05/2015 - 02/2007
3Lung Neoplasms (Lung Cancer)
08/2016 - 03/2009
2Carcinoma (Carcinomatosis)
07/2017 - 12/2003
2Cardiovascular Diseases (Cardiovascular Disease)
03/2016 - 03/2009
2Endometrial Neoplasms (Endometrial Cancer)
06/2012 - 03/2006
1Peripheral Arterial Disease
01/2022
1Hyperinsulinism (Hyperinsulinemia)
01/2022
1Obesity
02/2021
1Inflammation (Inflammations)
02/2021

Drug/Important Bio-Agent (IBA)

49Estrogens (Estrogen)FDA Link
11/2021 - 07/2002
41Estrogen ReceptorsIBA
01/2022 - 07/2002
28GTP-Binding Proteins (G-Protein)IBA
08/2020 - 12/2012
25Biological ProductsIBA
01/2022 - 07/2002
22G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
12/2018 - 06/2004
15Hormones (Hormone)IBA
01/2022 - 07/2002
14Estrogen Receptor alphaIBA
01/2020 - 07/2002
12LigandsIBA
04/2016 - 11/2002
11Proteins (Proteins, Gene)FDA Link
01/2022 - 05/2004
9Insulin-Like Growth Factor I (IGF-1)IBA
02/2021 - 08/2008
8Insulin (Novolin)FDA Link
01/2022 - 10/2014
8AndrogensIBA
12/2017 - 07/2002
7Pharmaceutical PreparationsIBA
01/2022 - 01/2011
7Aromatase (CYP19)IBA
05/2015 - 07/2002
6ErbB Receptors (EGF Receptor)IBA
01/2022 - 02/2007
6TamoxifenFDA LinkGeneric
07/2014 - 03/2006
5Androgen Receptors (Androgen Receptor)IBA
01/2022 - 11/2002
5Insulin ReceptorIBA
01/2022 - 01/2021
5MicroRNAs (MicroRNA)IBA
03/2019 - 06/2015
5SteroidsIBA
09/2013 - 11/2002
5Epidermal Growth Factor (EGF)IBA
08/2010 - 08/2008
4Growth Factor ReceptorsIBA
02/2019 - 12/2008
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2017 - 01/2013
4Transcription Factors (Transcription Factor)IBA
07/2017 - 03/2009
4Estradiol (Delestrogen)FDA LinkGeneric
01/2011 - 07/2002
4afimoxifene (hydroxytamoxifen)IBA
05/2010 - 03/2006
3Focal Adhesion Protein-Tyrosine KinasesIBA
06/2022 - 02/2019
3CytokinesIBA
11/2021 - 04/2016
3Biomarkers (Surrogate Marker)IBA
11/2021 - 01/2014
3IntegrinsIBA
02/2021 - 11/2010
3Collagen ReceptorsIBA
01/2021 - 02/2016
3Peptides (Polypeptides)IBA
01/2020 - 06/2017
3EnzymesIBA
12/2017 - 07/2002
3Fatty Acids (Saturated Fatty Acids)IBA
08/2017 - 11/2011
3IGF Type 1 Receptor (IGF 1 Receptor)IBA
08/2016 - 09/2009
3AtrazineIBA
04/2016 - 12/2008
3Oxygen (Dioxygen)IBA
03/2016 - 03/2011
3Connective Tissue Growth FactorIBA
01/2013 - 03/2009
3Messenger RNA (mRNA)IBA
08/2010 - 05/2004
3GenisteinIBA
10/2006 - 11/2002
2Progesterone Receptors (Progesterone Receptor)IBA
01/2022 - 01/2018
2Metformin (Glucophage)FDA LinkGeneric
01/2022 - 04/2014
2Protein Isoforms (Isoforms)IBA
11/2021 - 01/2021
2ChemokinesIBA
11/2021 - 06/2017
2Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
04/2021 - 01/2019
2Discoidin Domain Receptor 1IBA
01/2021 - 02/2016
2Somatomedin Receptors (Somatomedin Receptor)IBA
01/2021 - 01/2017
2ResveratrolIBA
10/2020 - 07/2009
2Furylfuramide (AF2)IBA
01/2020 - 01/2019
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
02/2019 - 02/2016
2Aromatase InhibitorsIBA
12/2018 - 07/2002
2LipidsIBA
01/2018 - 11/2011
2Hypoxia-Inducible Factor 1IBA
12/2017 - 01/2013
2CopperIBA
12/2017 - 10/2015
2Trace Elements (Biometals)IBA
12/2017 - 01/2017
2ZincIBA
12/2017 - 01/2017
2Doxycycline (Periostat)FDA LinkGeneric
09/2017 - 08/2017
2Vasoconstrictor AgentsIBA
02/2016 - 03/2009
2PesticidesIBA
05/2015 - 12/2008
2Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA
04/2014 - 09/2009
23,4-dihydroxyphenylethanol (hydroxytyrosol)IBA
03/2014 - 06/2010
2oleuropeinIBA
03/2014 - 06/2010
2titanoceneIBA
01/2014 - 06/2013
2Caveolin 1IBA
11/2013 - 07/2012
2bisphenol AIBA
08/2012 - 12/2003
2ElementsIBA
09/2010 - 02/2007
2Estrogen Receptor betaIBA
12/2008 - 06/2004
2QuercetinIBA
06/2004 - 11/2002
2Phytoestrogens (Phytoestrogen)IBA
06/2004 - 11/2002
2Steroid Receptors (Steroid Receptor)IBA
06/2004 - 12/2003
1FilaminsIBA
06/2022
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2022
1RNA (Ribonucleic Acid)IBA
11/2021
1Interleukin-11 (Interleukin 11)IBA
11/2021
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
02/2021
1Receptor for Advanced Glycation End ProductsIBA
02/2021
1AlarminsIBA
02/2021
1Type II DNA Topoisomerases (Topoisomerase II)IBA
10/2020
1Tyrosine Kinase InhibitorsIBA
10/2020
1Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
10/2020
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
10/2020
1Insulin-Like PeptidesIBA
01/2020

Therapy/Procedure

13Therapeutics
01/2022 - 06/2013
1Immunotherapy
01/2022